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KMID : 1143420220150302141
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Public Health Weekly Report
2022 Volume.15 No. 30 p.2141 ~ p.2157
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A comparative analysis of the types and characteristics of allergic rhinitis adult and child patients in the Republic of Korea
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Rha Yeong-Ho
Jeong Kyu-Tae
Chang Woo-Sung
Kim Young-Youl
Lee Hye-Ja
Hong Se-Hyang
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Abstract
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Allergic rhinitis (AR) is a disease that causes rhinorrhea, nasal stuffiness, sneezing, and itching in patients exposed to
inhaled antigens. The risk factors of AR are : genetic, having a family history of AR, excessive indoor/outdoor inhaled
antigens, and the environment. Although the prevalence of AR is increasing not only in the Republic of Korea (ROK) but also worldwide, there is a lack of research into the clinical features and characteristics of adult and child AR patients in the ROK. The National Institute of Health, Korea Centers for Disease Control and Prevention (KDCA) conducted a project to present basic data for analyzing the type and characteristics of AR in adults and children in the ROK.
The department of Pediatrics and Otolaryngology at the Seoul/Gyeonggi Regional Hospitals recruited AR patients to locate the phenotype and endotype of AR and collected medical information and blood sample data. In both adults and children with AR, the proportion of males was 65% higher than that of females, and the parents of children with AR had more allergic diseases such as AR and skin allergies than adults with AR. Children with AR had a higher history of respiratory diseases than adults, and eosinophils and IgE in the blood of children with AR were relatively increased compared toadults. Through this study, by confirming the phenotype and endotype of AR in adults and children, it can be used for personalized medicine. By identifying differences in therapeutic effect according to phenotypes, useful information can be presented for personalized treatment of AR in the ROK. Through additional data analysis and follow up of AR patients, more helpful information on the aggravating factors and the natural course of AR will be revealed.
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KEYWORD
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Allergic rhinitis (AR), Allergic rhinitis and its impact on asthma (ARIA) guideline, VAS score
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